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Further investigations of the IgE response to tetanus and diphtheria following covaccination with acellular rather than cellular Bordetella pertussis.

Rob C AalberseChristoph GrüberMargaretha LjungmanSuzan KakatUlrich WahnBodo NiggemannLennart Jan Nilsson
Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2020)
Cellular (but not acellular) B pertussis vaccine downregulates IgE to co-vaccinated antigens in infants. We assume that the absence of immediate-type allergic reactions is due to the high levels of IgG antibodies competing with IgE antibodies.
Keyphrases
  • atopic dermatitis