Ultrasmall Nanoparticle Delivery of Doxorubicin Improves Therapeutic Index for High-Grade Glioma.

Virginia Aragon-SanabriaAnusha Aditya Li ZhangFeng ChenBarney YooTianye CaoBrian MadajewskiRachel LeeMelik Z TurkerKai MaSebastien MonettePeiming ChenJing WuShutian RuanMichael OverholtzerPat ZanzonicoCharles M Rudin Cameron BrennanUlrich WiesnerMichelle S Bradbury

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Ultrasmall C' dot-drug conjugates showed great translational potential over DOX for improving the therapeutic outcome of patients with high-grade gliomas, even without a cancer-targeting moiety.

Keyphrases

high grade
low grade
iron oxide
cancer therapy
papillary thyroid
drug delivery
squamous cell carcinoma
human health
iron oxide nanoparticles
climate change
lymph node metastasis