Intracoronary recombinant tissue plasminogen activator in an infant with hypoplastic left heart syndrome and complete left main coronary artery thrombosis.
Bassel Mohmmad NijresJohn H HuntingtonGiedrius BaliulisJoseph J VettukattilPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2019)
An infant with hypoplastic left heart syndrome (HLHS) presented with complete heart block and severe myocardial dysfunction requiring ECMO support due to complete left main coronary artery (LMCA) thrombosis. Current guidelines for managing coronary artery thrombosis in infants with single ventricle physiology are inadequate. We describe successful LMCA and branch recanalization via intra coronary infusion of recombinant tissue plasminogen activator and discuss management of acute coronary thrombosis in children with single ventricle physiology.
Keyphrases
- coronary artery
- pulmonary artery
- pulmonary embolism
- heart failure
- atrial fibrillation
- pulmonary hypertension
- respiratory failure
- liver failure
- young adults
- case report
- mitral valve
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- drug induced
- coronary artery disease
- left ventricular
- pulmonary arterial hypertension
- early onset
- low dose
- congenital heart disease
- clinical practice
- percutaneous coronary intervention
- acute coronary syndrome
- mechanical ventilation
- aortic valve
- aortic stenosis