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Accelerating Prediction of Malignant Cerebral Edema After Ischemic Stroke with Automated Image Analysis and Explainable Neural Networks.

Hossein Mohammadian ForoushaniAli HamzehlooAtul KumarYasheng ChenLaura HeitschAgnieszka SlowikDaniel StrbianJin-Moo LeeDaniel S MarcusRajat Dhar
Published in: Neurocritical care (2021)
An LSTM neural network incorporating volumetric data extracted from routine CT scans identified all cases of malignant cerebral edema by 24 h after stroke, with significantly fewer false positives than a fully connected neural network, regression model, and the validated EDEMA score. This preliminary work requires prospective validation but provides proof of principle that a deep learning framework could assist in selecting patients for surgery prior to deterioration.
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