Overcoming tumor heterogeneity by ex vivo arming of T cells using multiple bispecific antibodies.
Jeong A ParkNai Kong V CheungPublished in: Journal for immunotherapy of cancer (2022)
Multi-EATs have the potential to increase potency, reduce toxicity, and overcome tumor heterogeneity without excessive cytokine release. Arming T cells with multiple BsAbs deserves further exploration to prevent or to treat cancer resistance.