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Sweet treats before sleep disrupt the clock system and increases metabolic risk markers in healthy rats.

Jorge R Soliz-RuedaRaúl López-Fernández-SobrinoHarriët SchellekensCristina Torres-FuentesLluis ArolaFrancisca Isabel BravoBegoña Mugureza
Published in: Acta physiologica (Oxford, England) (2023)
These results show that central clock genes and metabolic effects following a low dose of sugar are strongly time-dependent, causing higher circadian metabolic disruption when it is consumed at the beginning of the resting period, i.e., with the late-night snack.
Keyphrases
  • low dose
  • heart rate
  • sleep quality
  • genome wide
  • transcription factor
  • dna methylation
  • depressive symptoms
  • breast cancer risk