Cannabinoid receptors are expressed in equine synovium and upregulated with synovitis.

Ludovic MiagkoffChristiane A GirardGuillaume St-JeanHélène RichardGuy BeauchampSheila Laverty

Published in: Equine veterinary journal (2022)

Equine synovial intimal cells constitutively express both CB1 and CB2 receptors that are upregulated with synovitis and may have a role in joint pain. They are potential targets for therapy with cannabinoid molecules or their derivatives.

Keyphrases

induced apoptosis
chronic pain
cell cycle arrest
neuropathic pain
endoplasmic reticulum stress
cell death
stem cells
signaling pathway
cell proliferation
spinal cord
bone marrow
postoperative pain