Identification of Gm15441, a Txnip antisense lncRNA, as a critical regulator in liver metabolic homeostasis.

Mingyang XinQian GuoQingchun LuJuan LuPo-Shun WangYun DongTao LiYe ChenGlenn S GerhardXiao-Feng YangMichael AutieriLing Yang

Published in: Cell & bioscience (2021)

Our data demonstrate that Gm15441 is a potent Txnip inhibitor and a critical metabolic regulator in the liver. This study reveals the therapeutic potential of Gm15441 in treating metabolic diseases.

Keyphrases

nlrp inflammasome
transcription factor
electronic health record
anti inflammatory
long noncoding rna
bioinformatics analysis