Heredity of type 2 diabetes confers increased susceptibility to oxidative stress and inflammation.

Sonia BaigMuhammad ShabeerEhsan Parvaresh RiziMadhur AgarwalMichelle H LeeDelicia Shu Qin OoiChelsea ChiaNweni AungGeelyn NgYvonne TeoVanna ChhayFaidon MagkosAntonio Vidal-PuigRaymond C S SeetSue-Anne Ee Shiow Toh

Published in: BMJ open diabetes research & care (2021)

Our findings shed light on how heredity of T2DM confers increased susceptibility to oxidative stress and inflammation. This could provide early insights into the underlying mechanisms and future risk of FDRTs for developing T2DM and its associated complications.

Keyphrases

oxidative stress
diabetic rats
ischemia reperfusion injury
dna damage
induced apoptosis
risk factors
current status
glycemic control
type diabetes
heat shock
skeletal muscle
metabolic syndrome
signaling pathway
insulin resistance