ECCsplorer: a pipeline to detect extrachromosomal circular DNA (eccDNA) from next-generation sequencing data.

Ludwig Mann Kathrin M Seibt Beatrice Weber Tony Heitkam

Published in: BMC bioinformatics (2022)

The ECCsplorer (available online at https://github.com/crimBubble/ECCsplorer ) is a bioinformatics pipeline to detect eccDNAs in any kind of organism or tissue using next-generation sequencing data. The derived eccDNA targets are valuable for a wide range of downstream investigations-from analysis of cancer-related eccDNAs over organelle genomics to identification of active transposable elements.

Keyphrases

circulating tumor
electronic health record
copy number
big data
social media
circulating tumor cells
single molecule
machine learning
gene expression
data analysis
artificial intelligence
bioinformatics analysis
nucleic acid