Polymorphisms in the CYP2A6 and ABCC4 genes are associated with a protective effect on chronic myeloid leukemia in the Brazilian Amazon population.
Natasha MonteKarla Beatriz Cardias Cereja PantojaJuliana C G RodriguesDarlen C de CarvalhoTereza C B AzevedoEsdras E B PereiraPaulo P de AssumpçãoSidney E B Dos SantosMarianne R FernandesNey Pereira Carneiro Dos SantosPublished in: Molecular genetics & genomic medicine (2021)
Our findings suggest that the rs3742106 (ABCC4) and rs28399433 (CYP2A6) polymorphisms may modulate susceptibility to CML in a population of the Brazilian Amazon region.