Antioxidants: Scientific Literature Landscape Analysis.
Andy Wai Kan YeungNikolay T TzvetkovOsama S El-TawilSimona Gabriela BungauMohamed M Abdel-DaimAtanas Georgiev AtanasovPublished in: Oxidative medicine and cellular longevity (2019)
Antioxidants are abundant in natural dietary sources, and the consumption of antioxidants has a lot of potential health benefits. However, there has been no literature analysis on this topic to evaluate its scientific impact in terms of citations. This study is aimed at identifying and analysing the antioxidant publications in the existing scientific literature. In this context, a literature search was performed with the Web of Science database. Full records and cited references of the 299,602 identified manuscripts were imported into VOSviewer for bibliometric analysis. Most of the manuscripts were published since 1991. The publications were mainly related to the categories biochemistry/molecular biology, food science technology, and pharmacology/pharmacy. These topics have been prolific since 1990 and before. Polymer science was prolific before, but its publication share declined in the recent two decades. Brazil, China, India, and South Korea have emerged as upcoming major contributors besides USA. Most prolific journals were Food Chemistry, Journal of Agricultural and Food Chemistry, Free Radical Biology and Medicine, and PLOS One. Clinical conditions with high citations included Alzheimer's disease, cancer, cardiovascular disease, and Parkinson's disease. Chemical terms and structures with high citations included alpha-tocopherol, anthocyanin, ascorbate, beta-carotene, carotenoid, curcumin, cysteine, flavonoid, flavonol, hydrogen peroxide, kaempferol, N-acetylcysteine, nitric oxide, phenolic acid, uric acid, vitamin C, vitamin E, selenium, and resveratrol. Citation patterns temporal analysis revealed a transition of the scientific interest from research focused on antioxidant vitamins and minerals into stronger attention focus on antioxidant phytochemicals (plant secondary metabolites).
Keyphrases
- hydrogen peroxide
- nitric oxide
- cardiovascular disease
- systematic review
- public health
- uric acid
- human health
- oxidative stress
- metabolic syndrome
- coronary artery disease
- squamous cell carcinoma
- emergency department
- single cell
- climate change
- type diabetes
- cardiovascular events
- health promotion
- cognitive decline
- mild cognitive impairment
- drug discovery
- cell wall
- adverse drug