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Genetic Diversity of Leishmania major Isolated from Different Dermal Lesions Using ITS2 Region.

Ruaa M KhazalMohammed H FlaihManar K KadhimKhwam R Hussein
Published in: Acta parasitologica (2024)
ITS2-PCR is suitable for identifying Leishmania spp. and determining genetic diversity. A phylogenetic data analysis may provide an idea on the genetic homogeneity of local isolates and knowing the genetic origin of the dermal lesion. However, the local isolates showed genetic proximity to the KU680848.1 isolate. This signifies the possibility of infection prevalence from Iranian areas. In general, genetic variation of L. major isolates may give several clinical manifestations of the cutaneous lesion. Therefore, determination of the heterogeneity is important for detecting the infection origin, epidemiology, therapy, and control strategies.
Keyphrases
  • genetic diversity
  • data analysis
  • genome wide
  • risk factors
  • copy number
  • stem cells
  • cell therapy
  • mesenchymal stem cells
  • molecularly imprinted
  • functional connectivity