Comprehensive analysis of early T cell responses to acute Zika Virus infection during the first epidemic in Bahia, Brazil.
Assia SamriAntônio Carlos de Albuquerque BandeiraLuana Leandro GoisCarlos Gustavo Regis SilvaAlice RousseauAurelien CorneauNadine TarantinoChristopher MaucourantGabriel Andrade Nonato QueirozVincent VieillardHans YsselGubio Soares CamposSilvia SardiBrigitte AutranMaria Fernanda Rios GrassiPublished in: PloS one (2024)
Circulating T lymphocytes spontaneously produce IFN-γ and express elevated levels of pSTAT-5 during the early phase of ZIKV infection whereas recognition of ZIKV antigen results in the generation of virus-specific IFN-γ-producing T cells.