A nationwide genomic study of clinical Klebsiella pneumoniae in Norway 2001-15: introduction and spread of ESBLs facilitated by clonal groups CG15 and CG307.

Aasmund FostervoldMarit Andrea Klokkhammer HetlandRagna BakksjøEva BernhoffKathryn E Holt Ørjan SamuelsenGunnar Skov SimonsenArnfinn SundsfjordKelly L WyresIren Høyland Löhrnull null

Published in: The Journal of antimicrobial chemotherapy (2022)

The increase in Norwegian ESBL-producing KpSC during 2010-15 was driven by CG307 and CG15 carrying blaCTX-M-15. K. variicola ssp. variicola was a frequent cause of invasive KpSC infection, but rarely carried ESBLs.

Keyphrases

klebsiella pneumoniae
escherichia coli
multidrug resistant
copy number
gene expression