High-intensity interval training in hypoxia does not affect muscle HIF responses to acute hypoxia in humans.

Stefan De SmetGommaar D'HulstChiel PofféRuud Van ThienenEmanuele BerardiPeter Hespel

Published in: European journal of applied physiology (2018)

Ten minutes of arterial occlusion increased HIF-1α-expressing myonuclei. However, neither normoxic nor hypoxic training during 'living high' altered muscle HIF translocation, stabilisation, or transcription in response to acute hypoxia induced by arterial occlusion.

Keyphrases

endothelial cells
liver failure
respiratory failure
skeletal muscle
drug induced
aortic dissection
virtual reality
mechanical ventilation
acute respiratory distress syndrome