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Immunoinformatics-Based Identification of B and T Cell Epitopes in RNA-Dependent RNA Polymerase of SARS-CoV-2.

Shabir Ahmad MirMohammed A AlaidarousBader Mohammed AlshehriAbdul Aziz Bin DukhyilSaeed S BanawasYahya MadkhaliSuliman Abdallah AlsagabyAyoub Al Othaim
Published in: Vaccines (2022)
These findings suggest that our designed multi-epitope vaccine possessing intrinsic T cell and B cell epitopes with high antigenicity scores could be considered for the ongoing development of peptide-based novel vaccines against COVID-19. However, further in vitro and in vivo studies need to be performed to confirm our in silico observations.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • coronavirus disease
  • molecular docking
  • case control
  • monoclonal antibody