Chemical Constituents from Berchemia polyphylla var. Leioclada.

One previously undescribed naphthoquinone-benzisochromanquinone dimer berpolydiquinone A ( 1 ), along with two previously undescribed naphthoquinone-anthraquinone dimers berpolydiquinones B and C ( 2 - 3 ), and one previously undescribed dimeric naphthalene berpolydinaphthalene A ( 4 ), were isolated from the stems and leaves of Berchemia polyphylla var. leioclada. The chemical structures of these compounds were determined using high-resolution electrospray ionization mass spectroscopy (HR-ESI-MS), spectroscopic data, the exciton chirality method (ECM), and quantum chemical calculation. Notably, compounds ( 1 - 2 and 5 ) are dimeric quinones that share the same naphthoquinone moiety, specifically identified as 2-methoxystypandron. Compound ( 4 ) is a derivative of dimeric naphthalene with a symmetrical structure, which is a new structure type isolated from B. polyphylla var. leioclada for the first time. These findings suggest that B. polyphylla var. leioclada serves as a significant reservoir of structurally diverse phenolic compounds. This study provides a scientific foundation for regarding B. polyphylla var. leioclada as a potential source of "Tiebaojin".