Predictors of Plasma Levels of Direct Oral Anticoagulants Among Patients with Atrial Fibrillation in Need of Elective Cardiac Procedures.

Vincenzo RussoEleonora CaiazzaFiorella Chiara Delle FemineEnrica PezzulloSara SarpaAntonio IannicielloCaturano AlfredoAntonello D'AndreaPaolo GolinoGerardo Nigro

Published in: Cardiovascular drugs and therapy (2024)

Increased creatinine clearance and inappropriate longer drug withdrawal period are the only independent predictors of DOAC plasma levels below the reference range; in contrast, diabetes is significantly correlated with DOAC plasma levels above the reference.

Keyphrases

direct oral anticoagulants
venous thromboembolism
atrial fibrillation
type diabetes
cardiovascular disease
magnetic resonance
patients undergoing
left ventricular
uric acid
emergency department
metabolic syndrome
heart failure
skeletal muscle
adipose tissue
contrast enhanced
drug induced
insulin resistance