Switching within versus out of class following first-line TNFi failure in ulcerative colitis: real-world outcomes from a German claims data analysis.

Evi ZhulekuDaniel WirthRiikka NissinenIvana BravatàDespina ZiavraAndreas DuvaJennifer LeeAndreas FuchsSabrina MuellerThomas WilkeBernd Bokemeyer

Published in: Therapeutic advances in gastroenterology (2024)

Following first-line TNFi failure, this study suggests that real-world outcomes among patients with UC are less favorable when cycling to another TNFi, compared to switching to a non-TNFi such as UST or VDZ.

Keyphrases

data analysis
ulcerative colitis
health insurance
high intensity
metabolic syndrome
skeletal muscle
insulin resistance