Optimising alkalinisation and its effect on QRS narrowing in tricyclic antidepressant poisoning.
Kieran PaiNicholas Alan BuckleyKatherine Z IsoardiGeoffrey K IsbisterTherese BeckerAngela Lin ChiewRose CairnsJared A BrownBetty S H ChanPublished in: British journal of clinical pharmacology (2021)
A combination of NaHCO3 and mechanical ventilation was most effective in achieving serum alkalinisation and was associated with a more rapid narrowing of the QRS interval. We advise that the maximal dose of NaHCO3 should be <400 mmol (6 mmol/kg).
Keyphrases
- mechanical ventilation
- cardiac resynchronization therapy
- acute respiratory distress syndrome
- intensive care unit
- major depressive disorder
- respiratory failure
- heart rate
- heart failure
- left ventricular
- extracorporeal membrane oxygenation
- loop mediated isothermal amplification
- blood pressure
- bipolar disorder
- body composition