Obesity Is Associated with Attenuated Tissue Immunity in COVID-19.
Shuang Andrew GuoGeorgina S BowyerJohn R FerdinandMailis MaesZewen K TuongEleanor GillmanMingfeng LiaoRik G H LindeboomMasahiro YoshidaKaylee WorlockHudaa GopeeEmily StephensonCatherine A GaoPaul A LyonsKenneth G C SmithMuzlifah HaniffaKerstin B MeyerMarko Z NikolićZheng ZhangRichard G WunderinkAlexander V MisharinGordon DouganVilas NavapurkarSarah A TeichmannAndrew Conway MorrisMenna R ClatworthyPublished in: American journal of respiratory and critical care medicine (2022)
These findings show blunted tissue immune responses in Ob COVID-19 patients, with implications for treatment stratification, supporting the specific application of inhaled recombinant type I IFNs in this vulnerable subset. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).