Efficacy and safety of Propionibacterium extract gel versus glyceryl trinitrate ointment in the treatment of chronic anal fissure: a randomized controlled trial.
Gaetano GalloMario TrompettoSerena FulginitiMarco La TorreSimone TiernoFrancesco CantarellaPaolo VaniniGiovanni TomasicchioDonato Francesco AltomareMarcella RinaldiGiulio Aniello SantoroGiuseppe CurròUgo GrossiPublished in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2023)
While there was no difference in healing rates between the two treatments, PeG was more cost-effective and associated with fewer adverse events.