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A Multicenter Randomized Phase II Study of Single Agent Efficacy and Optimal Combination Sequence of Everolimus and Pasireotide LAR in Advanced Thyroid Cancer.

Julie E BaumanZhengjia ChenChao ZhangJames P OhrRobert L FerrisGerald M McGoriskStephen BrandtSumathi SrivatsaAmy Y ChenConor E SteuerDong M ShinNabil F SabaFadlo R KhuriTaofeek Kunle Owonikoko
Published in: Cancers (2022)
The combination of everolimus and pasireotide-LAR showed promising efficacy over single agent. The delayed combination of everolimus and pasireotide-LAR following progression on single agent everolimus appeared intriguing as a combination strategy.
Keyphrases
  • phase ii study
  • open label
  • double blind
  • placebo controlled
  • squamous cell carcinoma
  • phase iii
  • locally advanced
  • amino acid