Rosuvastatin alleviates high-salt and cholesterol diet-induced cognitive impairment in rats via Nrf2-ARE pathway.

Ibraheem HusainMohd AkhtarTushar MadaanMalik Zainul AbdinMohammad IslamuddinAbul Kalam Najmi

Published in: Redox report : communications in free radical research (2018)

We have investigated a novel mechanism of action for rosuvastatin (via the Nrf2-ARE pathway) and demonstrated that it has the potential to be used in the treatment of cognitive impairment.

Keyphrases

cognitive impairment
oxidative stress
atomic force microscopy
high resolution