Cytoplasm protein GFAP magnetic beads construction and application as cell separation target for brain tumors.

Yang ZhaoFeng JiangQinhua WangBaocheng WangYipeng HanJian YangJiajia WangKai WangJunping AoXunxiang GuoXiaofei LiangJie Ma

Published in: Journal of nanobiotechnology (2020)

The results indicated that GFAP-IML CTCs isolation system, combined with an EGFR immunofluorescence assay of antitumor marker, can serve as a brand-new method for the identification of CTCs for brain tumors. Via lumbar puncture, a minimally invasive procedure, this technique may play a significant role in the clinical diagnosis and drug evaluation of brain tumors.

Keyphrases

minimally invasive
circulating tumor cells
small cell lung cancer
single cell
robot assisted
epidermal growth factor receptor
high throughput
tyrosine kinase
cell therapy
ultrasound guided
bioinformatics analysis
mesenchymal stem cells
bone marrow
small molecule
drug induced