l-Citrulline ameliorates pathophysiology in a rat model of superimposed preeclampsia.

Andy W C ManYawen ZhouUyen D P LamGisela ReifenbergAnke WernerAlice HabermeierEllen I Closs Andreas DaiberThomas MünzelNing Xia Huige Li

Published in: British journal of pharmacology (2022)

This study shows that l-citrulline supplementation reduced gestational hypertension and improved placentation and fetal growth in a rat model of superimposed preeclampsia. l-Citrulline supplementation may provide an effective and safe therapeutic strategy for preeclampsia that benefits both the mother and the fetus.

Keyphrases

early onset
pregnancy outcomes
blood pressure
pregnant women
weight gain
body mass index
birth weight
preterm birth