α-Synuclein oligomers potentiate neuroinflammatory NF-κB activity and induce Ca v 3.2 calcium signaling in astrocytes.
Emmanouela LeandrouIoanna ChalatsaDimitrios AnagnostouChristina MachaliaMaria SemitekolouVicky FilippaManousos MakridakisAntonia VlahouEma AnastasiadouKostas VekrellisEvangelia EmmanouilidouPublished in: Translational neurodegeneration (2024)
3.2 channels as a potential neuroprotective mediator against the α-synuclein-induced neuroinflammation.
Keyphrases
- lps induced
- cerebral ischemia
- signaling pathway
- high glucose
- diabetic rats
- oxidative stress
- traumatic brain injury
- lipopolysaccharide induced
- inflammatory response
- nuclear factor
- pi k akt
- cognitive impairment
- drug induced
- subarachnoid hemorrhage
- human health
- protein kinase
- brain injury
- risk assessment
- cell proliferation
- toll like receptor