Multidimensional outcome assessment of pulmonary rehabilitation in traits-based clusters of COPD patients.
Ingrid M L AugustinFrits M E FranssenSarah Houben-WilkeDaisy J A Janssen Nienke NakkenSwetlana GaffronHerman-Jan PenningsFrank W J M SmeenkWillem R PietersAmber HoogerwerfArent-Jan MichelsFrits van MerodeEmiel F M WoutersMartijn A. SpruitPublished in: PloS one (2022)
The current study confirms the differential response to pulmonary rehabilitation based on multidimensional response profiling. Cluster analysis of baseline traits illustrates that non-linear, clinically important differences can be achieved in the most functionally and emotionally impaired clusters and that 'the overall best functional cluster' as well as 'the low disease burden cluster' had an attenuated outcome.