Cellular immune responses in amniotic fluid of women with preterm labor and intra-amniotic infection or intra-amniotic inflammation.
Nardhy Gomez-LopezRoberto RomeroJose GalazYi XuBogdan PanaitescuRebecca SlutskyKenichiro MotomuraNavleen GillRobert ParaPercy PacoraEunjung JungChaur-Dong HsuPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2019)
The cellular immune responses observed in women with preterm labor and intra-amniotic infection are more severe than in those with intra-amniotic inflammation, and neutrophils, monocytes/macrophages, and CD4+ T cells are the main immune cells responding to microorganisms that invade the amniotic cavity. These findings provide insights into the intra-amniotic immune mechanisms underlying the human syndrome of preterm labor.