Has the time come to stop routine N-acetylcysteine treatment in young children in Denmark? A review of 300 suspected paracetamol overdoses in children aged 0-6 years.

This study shows that initiating N-acetylcysteine as a "one size fit all" treatment regimen in all children aged 0-6 years with a suspected single paracetamol overdose leads to substantial overtreatment. The data supports that it is feasible to initiate N-acetylcysteine within 10 hours based on an early plasma-paracetamol test.