N-acetylcysteine regulates dental follicle stem cell osteogenesis and alveolar bone repair via ROS scavenging.

Zhaosong Meng Jiacheng LiuZhipeng FengShuling GuoMingzhe WangZheng WangZhe LiHongjie LiLei Sui

Published in: Stem cell research & therapy (2022)

The proper concentration of NAC enhances DFSC properties, especially osteogenesis, via PI3K/AKT/ROS signaling, and offers clinical potential for stem cell-based alveolar bone regeneration.

Keyphrases

bone regeneration
stem cells
pi k akt
signaling pathway
cell death
cell cycle arrest
dna damage
cell proliferation
reactive oxygen species
transcription factor
cell therapy
oral health
bone mineral density
mesenchymal stem cells
body composition
bone marrow
climate change