Out of sight: a lesson in drug errors.
Soon Tjin LimTimothy YatesDi LiangHeather Angus-LeppanPublished in: Practical neurology (2020)
A 76-year-old man developed recurrent encephalopathy, visual disturbance, myoclonus, generalised seizures and atonic drop attacks on a background of a gastrectomy for adenocarcinoma and stable chronic lymphocytic leukaemia. He presented to three different hospitals and was admitted twice, with normal investigations. His symptoms transiently improved during each admission (and with starting levetiracetam) but recurred each time on hospital discharge. Subsequent careful inspection of his medication box identified that his community pharmacy had in error been dispensing baclofen 80 mg per day instead of his prescribed Buscopan 80 mg per day. This case highlights the importance of physically inspecting a patient's medications and emphasises the spectrum of baclofen-related toxicity; it also highlights potential deficiencies in the pharmacy dispensary process and the need for multiple checks by patients and professionals.
Keyphrases
- healthcare
- end stage renal disease
- adverse drug
- ejection fraction
- newly diagnosed
- emergency department
- squamous cell carcinoma
- chronic kidney disease
- mental health
- oxidative stress
- prognostic factors
- transcription factor
- early onset
- case report
- depressive symptoms
- physical activity
- risk assessment
- patient reported outcomes
- rectal cancer
- quality improvement