Impact of osteopontin on the development of non-alcoholic liver disease and related hepatocellular carcinoma.
Alexander D NardoNicole G GrünMaximilian ZeydaMonika DumanicGeorg OberhuberElisa RivellesThomas H HelbichDaniel F MarkgrafMichael RodenThierry ClaudelMichael TraunerThomas M StulnigPublished in: Liver international : official journal of the International Association for the Study of the Liver (2020)
Lack of osteopontin dissociates NASH-fibrosis severity from overall survival and HCC malignant transformation in NAFLD, and is therefore a putative therapeutic target only for advanced chronic liver disease.
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