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Comparative genomic analysis of the Hafnia genus reveals an explicit evolutionary relationship between the species alvei and paralvei and provides insights into pathogenicity.

Zhiqiu YinChao YuanYuhui DuPan YangChengqian QianYi WeiSi ZhangDi HuangBin Liu
Published in: BMC genomics (2019)
Our research using core genome phylogeny and comparative genomics analysis of a larger collection of strains provides a comprehensive view of the taxonomy and species-specific traits between Hafnia species. Deciphering the genome of Hafnia strains possessing a reservoir of macromolecular secretion systems, virulence factors, and resistance genes related to pathogenicity may provide insights into addressing its numerous infections and devising strategies to combat the pathogen.
Keyphrases
  • genome wide
  • escherichia coli
  • biofilm formation
  • pseudomonas aeruginosa
  • dna methylation
  • genetic diversity
  • single cell
  • candida albicans
  • gene expression
  • cystic fibrosis
  • bioinformatics analysis