Cardiac remodelling in the highest city in the world: effects of altitude and chronic mountain sickness.
Stephane DoutreleauMathilde Ulliel-RocheIvan HanccoJean-François TimsitLaura OberholzerPaul RobachJulien V BrugniauxAurélien PichonEmeric StaufferElisa PergerGianfranco ParatiSamuel VergesPublished in: European journal of preventive cardiology (2022)
Healthy dwellers at 5100 m exhibit both right heart dilatation and left ventricle concentric remodelling with diastolic dysfunction. Those modifications are even more pronounced in moderate-severe CMS subjects and could represent the limit of the heart's adaptability before progression to heart failure.