Upregulated dual oxidase 1-induced oxidative stress and caspase-1-dependent pyroptosis reflect the etiologies of heart failure.
Yan Song LiJingwen XiaChang Yuan ChenShu Hong RenMao Rong He
Published in: BMC molecular and cell biology (2024)
These results suggest that DUOX1-derived genotoxicity could promote heart failure development. In the process, oxidative stress and pyroptosis may be involved in the regulation of DUOX1 in heart failure.