INSULIN AND INSULIN RECEPTOR GENE POLYMORPHISMS AND SUSCEPTIBILITY TO NONALCOHOLIC FATTY LIVER DISEASE.
Hossein NobakhtTouraj MahmoudiMohammad SabzikarianSeidamir Pasha TabaeianGholamreza RezamandAsadollah AsadiHamid FarahaniReza DabiriFariborz Mansour-GhanaeiIradj MalekiMohammad Reza ZaliPublished in: Arquivos de gastroenterologia (2020)
These findings corroborate the hypothesis that genetic polymorphisms related to insulin resistance play a role in NAFLD susceptibility. Specifically, the INSR rs1799817 "TT" genotype had a protective effect for NAFLD. However, our results remain to be validated in other studies.