The Effect of Sumatriptan in Ischemic Conditions in the Rat Heart.

Hande Özge Altunkaynak-Çamca Müge Tecder-Ünal Meral Tuncer

Published in: Turkish journal of pharmaceutical sciences (2018)

SUM protects the heart against IR injury but is not as protective as IPC alone. Although SUM diminishes IPC-induced protection against VT, the preventive effect of SUM against VF may be predictive for cardioprotection in ischemic conditions.

Keyphrases

heart failure
ischemia reperfusion injury
high glucose
atrial fibrillation
diabetic rats
oxidative stress
cerebral ischemia
drug induced
endothelial cells