Effect of Rubus anatolicus Leaf Extract on Glucose Metabolism in HepG2, CRI-D2 and C2C12 Cell Lines.

Mahdieh SafarzadAbdoljalal MarjaniMarie Saghaeian JaziDurdi QujeqSeyed Mostafa MirMajid MarjaniAbbas Nezhadebrahimi Kaldehi

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2020)

The R. anatolicus appears to activate glucose uptake and cellular glycogen synthesis probably by activating the glycogenesis or inhibition of glycogenolysis pathways. The extract enhances insulin secretion in the pancreatic cells by increased glucose uptake.

Keyphrases

induced apoptosis
blood glucose
signaling pathway
cell cycle arrest
oxidative stress
cell death
type diabetes
blood pressure