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Human mesenchymal stem cells in the tumour microenvironment promote ovarian cancer progression: the role of platelet-activating factor.

Tong GaoYi YuQing CongYisheng WangMingming SunLiangqing YaoCongjian XuWei Jiang
Published in: BMC cancer (2018)
Our results suggest that the tumour-promoting effect of MSCs on OCCs via their cross-talk in the tumour microenvironment was, at least in part, mediated by the PAF/PAFR pathway, suggesting a new target for the treatment of ovarian cancer.
Keyphrases
  • mesenchymal stem cells
  • stem cells
  • umbilical cord
  • endothelial cells
  • bone marrow
  • induced pluripotent stem cells