Sex Differences in Characteristics, Outcomes and Treatment Response with Dapagliflozin across the Range of Ejection Fraction in Patients with Heart Failure: Insights from DAPA-HF and DELIVER.
Xiaowen WangMuthiah VaduganathanBrian Lee ClaggettSheila M HegdeMaria PabonIan J KulacOrly VardenyEileen O'MearaShelley ZierothTzvetana KatovaMartina M McGrathAnne-Catherine PouleurPardeep S JhundAkshay S DesaiCatherine M ViscoliMikhail Naum KosiborodRudolf A de BoerLars Valeur KøberMarc S SabatineFelipe A MartinezPiotr PonikowskiSanjiv J ShahAdrian F HernandezAnna Maria LangkildeJohn Joseph Valentine McMurrayScott D SolomonCarolyn Su Ping LamPublished in: Circulation (2022)
In DAPA-HF and DELIVER, the response to dapagliflozin was similar between men and women. Sex did not modify the treatment effect of dapagliflozin across the range of ejection fraction.