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Epidemiology and Management of Infections in Liver Transplant Recipients.

Waseem AmjadSyed Hamaad RahmanThomas D SchianoSyed-Mohammed Jafri
Published in: Surgical infections (2024)
Background: Improvements in liver transplant (LT) outcomes are attributed to advances in surgical techniques, use of potent immunosuppressants, and rigorous pre-LT testing. Despite these improvements, post-LT infections remain the most common complication in this population. Bacteria constitute the most common infectious agents, while fungal and viral infections are also frequently encountered. Multi-drug-resistant bacterial infections develop because of polymicrobial overuse and prolonged hospital stays. Immediate post-LT infections are commonly caused by viruses. Conclusions: Appropriate vaccination, screening of both donor and recipients before LT and antiviral prophylaxis in high-risk individuals are recommended. Antimicrobial drug resistance is common in high-risk LT and associated with poor outcomes; epidemiology and management of these cases is discussed. Additionally, we also discuss the effect of coronavirus disease 2019 (COVID-19) infection and monkeypox in the LT population.
Keyphrases
  • drug resistant
  • coronavirus disease
  • risk factors
  • staphylococcus aureus
  • emergency department
  • acinetobacter baumannii
  • type diabetes
  • pseudomonas aeruginosa
  • electronic health record