Electroacupuncture Reduces Weight in Diet-Induced Obese Rats via Hypothalamic Tsc1 Promoter Demethylation and Inhibition of the Activity of mTORC1 Signaling Pathway.
Jincheng LengFeng XiongJunpeng YaoXiahuan DaiYulei LuoMaoqing HuLin ZhangYing LiPublished in: Evidence-based complementary and alternative medicine : eCAM (2018)
Our study could shed light on the potential pathway where EA exerts effects on the mechanism of EA treatment for obesity through the hypothalamic Tsc1 promoter demethylation and inhibition of the activity of mTORC1 signaling pathway.
Keyphrases
- signaling pathway
- weight loss
- metabolic syndrome
- dna methylation
- pi k akt
- type diabetes
- gene expression
- weight gain
- transcription factor
- insulin resistance
- adipose tissue
- bariatric surgery
- body mass index
- induced apoptosis
- neuropathic pain
- obese patients
- spinal cord injury
- spinal cord
- skeletal muscle
- blood brain barrier
- endoplasmic reticulum stress