5-HTTLPR-brain-derived neurotrophic factor (BDNF) gene interactions and early adverse life events effect on impulsivity in suicide attempters.

Luis Jiménez-TreviñoPilar Alejandra SaizMaria Paz García-PortillaHilario Blasco-FontecillaVladimir CarliMiriam IosueIsabelle JaussentJorge Lopez CastromanConcepcion Vaquero-LorenzoMarco SarchiaponeEnrique Baca-GarciaPhilippe CourtetJulio Bobes

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2017)

Childhood trauma and 5-HTTLPR genotype seem to be independently involved in suicide attempts, sharing a common pathway of increasing impulsivity.

Keyphrases

obsessive compulsive disorder
borderline personality disorder
copy number
social media
genome wide
gene expression
childhood cancer
transcription factor
electronic health record
genome wide analysis