Downregulation of Tumor Promotor Genes in Oryza Sativa Linn.-Induced Antiproliferative Activity of Human Squamous Carcinoma Cells.

Petchpailin Leenutaphong Salunya TancharoenKiyoshi KikuchiThamthiwat NararatwanchaiChareerut PhruksaniyomSirintip Chaichalotornkul

Published in: Asian Pacific journal of cancer prevention : APJCP (2023)

Together, these results indicate that OS can inhibit HSC-2 cell proliferation and this may involve TGF-β1 downregulation. Thus, this study shows OS could be useful for the treatment of patients with squamous carcinoma.

Keyphrases

cell proliferation
high grade
endothelial cells
high glucose
signaling pathway
low grade
cell cycle
genome wide
diabetic rats
transforming growth factor
pi k akt
induced pluripotent stem cells
dna methylation
gene expression
combination therapy
bioinformatics analysis
stress induced