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Novel loci for ocular axial length identified through extreme-phenotype genome-wide association study in Chinese populations.

Xiaotong HanSiyu PanJialin LiuXiaohu DingXingyan LinDecai WangZhi XieChangqing ZengFan LiuMingguang HeXiangtian ZhouTianzi LiuLixia LuoYizhi Liu
Published in: The British journal of ophthalmology (2023)
Our study identified two population-specific novel loci for AL, expanding our understanding of the genetic basis of AL and providing evidence for a role of the nervous system and glucose metabolism in myopia pathogenesis.
Keyphrases
  • genome wide association study
  • genome wide
  • climate change
  • optic nerve
  • gene expression