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Pictet-Spengler Synthesis of N-Heteroaromatics Extended Porphyrins.

Dileep Kumar Singh
Published in: Current organic synthesis (2023)
This review provides a comprehensive overview of the synthesis of N-heterocyclic extended porphyrins and metalloporphyrins via a modified Pictet-Spengler approach. The synthesized porphyrins were found to be highly conjugated and exhibited improved photophysical properties compared to their parent analogues. Moreover, the review article provided a brief overview of the Pictet-Spengler procedure, including product yields, reaction conditions, photophysical properties of the synthesized products, and potential applications in a variety of fields.
Keyphrases
  • photodynamic therapy
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  • structure activity relationship