Psoriasis and progression of Parkinson's disease: a Mendelian randomization study.

Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2022)

These results suggested psoriasis accelerated overall progression of PD, and increased risk of dementia and depression of PD. A deeper understanding of neuroinflammation and immune response is likely to elucidate the potential pathogenesis of PD progression and identify novel therapeutic targets.

Keyphrases

immune response
cognitive impairment
depressive symptoms
lipopolysaccharide induced
atopic dermatitis
sleep quality
risk assessment
inflammatory response
cerebral ischemia
subarachnoid hemorrhage