A comparison of DNA methylation in newborn blood samples from infants with and without orofacial clefts.

Zongli XuRolv T LieAllen J WilcoxOla Didrik SaugstadJack A Taylor

Published in: Clinical epigenetics (2019)

We identified two individual CpGs and multiple DMRs that differ between controls and cleft case subtypes. Although we find some evidence for the possible role of DNA methylation in etiology of orofacial clefts, our study does not support previous reports of widespread differences in blood DNA methylation between babies with and without facial clefts.

Keyphrases

dna methylation
genome wide
gene expression
adverse drug